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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP20A1
All Species:
19.7
Human Site:
S255
Identified Species:
36.11
UniProt:
Q6UW02
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UW02
NP_803882.1
462
52432
S255
S
Q
H
I
F
I
D
S
L
V
Q
G
N
L
N
Chimpanzee
Pan troglodytes
Q8HYN1
508
57365
Q282
N
G
N
A
G
P
D
Q
D
S
E
L
L
S
D
Rhesus Macaque
Macaca mulatta
XP_001105388
458
51229
G255
F
I
D
S
L
V
Q
G
N
L
N
D
Q
Q
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKE6
462
52131
S255
R
Q
H
T
F
I
D
S
L
T
Q
G
K
L
N
Rat
Rattus norvegicus
Q6P7D4
462
51979
S255
S
Q
H
T
F
I
D
S
L
V
Q
R
N
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506190
262
29719
N62
S
L
L
Q
G
N
L
N
D
K
Q
V
L
E
D
Chicken
Gallus gallus
XP_426572
463
52409
T256
N
R
H
V
F
I
D
T
L
L
Q
G
N
L
S
Frog
Xenopus laevis
NP_001079548
463
52021
S256
G
R
H
V
F
L
D
S
L
L
Q
G
N
L
S
Zebra Danio
Brachydanio rerio
NP_998497
462
51647
Y255
S
S
Q
S
F
V
N
Y
L
L
Q
A
N
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXY0
495
57171
M280
R
R
L
A
F
L
D
M
L
L
L
T
Q
M
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792896
231
25756
T31
P
T
T
P
Q
K
T
T
T
V
P
G
L
E
P
Poplar Tree
Populus trichocarpa
XP_002300926
460
52070
D256
E
G
G
E
D
Q
E
D
K
L
T
D
K
Q
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65790
500
57537
Q280
H
L
I
S
L
Q
Q
Q
Q
P
E
Y
Y
T
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.2
60.6
N.A.
N.A.
83.1
81.8
N.A.
42.6
73.6
73.2
63.8
N.A.
21
N.A.
N.A.
23.1
Protein Similarity:
100
42.7
65.8
N.A.
N.A.
90.6
91.1
N.A.
50.6
88.7
88.3
81.5
N.A.
38.7
N.A.
N.A.
36.3
P-Site Identity:
100
6.6
0
N.A.
N.A.
73.3
86.6
N.A.
13.3
60
60
40
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
33.3
13.3
N.A.
N.A.
73.3
86.6
N.A.
26.6
100
93.3
60
N.A.
46.6
N.A.
N.A.
20
Percent
Protein Identity:
23.8
N.A.
N.A.
22.4
N.A.
N.A.
Protein Similarity:
42.8
N.A.
N.A.
42.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
54
8
16
0
0
16
0
0
24
% D
% Glu:
8
0
0
8
0
0
8
0
0
0
16
0
0
16
8
% E
% Phe:
8
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
16
8
0
16
0
0
8
0
0
0
39
0
0
0
% G
% His:
8
0
39
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
8
0
31
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
8
0
0
8
8
0
0
16
0
0
% K
% Leu:
0
16
16
0
16
16
8
0
54
47
8
8
24
47
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
16
0
8
0
0
8
8
8
8
0
8
0
39
0
24
% N
% Pro:
8
0
0
8
0
8
0
0
0
8
8
0
0
0
8
% P
% Gln:
0
24
8
8
8
16
16
16
8
0
54
0
16
16
0
% Q
% Arg:
16
24
0
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
31
8
0
24
0
0
0
31
0
8
0
0
0
8
16
% S
% Thr:
0
8
8
16
0
0
8
16
8
8
8
8
0
8
8
% T
% Val:
0
0
0
16
0
16
0
0
0
24
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _